87 Treatment of Idiopathic Nonhistaminergic Angiodema with Icatibant

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87 Treatment of Idiopathic Nonhistaminergic Angiodema with Icatibant

severe abdominal edema; edema of face, neck, or lips and severe edema of the extremities and trunk. Clinical and laboratory data were entered into the Hungarian HAE Registry. Results: 152 attacks out of 1392 experienced by 42 patients were treated with C1-INH concentrate (28% of attacks at home and 72% at the clinic). The distribution of C1-INH-treated attacks by location was as follows: 38% su...

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Treatment with icatibant in the management of drug induced angioedema.

Acute, drug-induced angioedema may not respond to standard therapies, because the pathogenetic mechanism that induces the pathology is not always mediated by histamine but, in certain instances, by bradykinin. A case of angioedema is reported here, in which allergic etiology was excluded by the non-response to antihistamines. Considering the clinical history (repeated use of drugs) and the inef...

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Treatment of angiotensin-converting enzyme inhibitor related angioedema with icatibant

Background The absolute risk of angiotensin-converting enzyme (ACE) inhibitor angioedema is 0.3% [1]. The mechanism is felt to be accumulation of bradykinin. The current treatment is discontinuation of ACE-I inhibitor, and intubation if necessary. Icatibant is a bradykinin receptor antagonist, useful in treating hereditary angioedema [2]. We present a patient from a Canadian center who had ACE-...

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ژورنال

عنوان ژورنال: World Allergy Organization Journal

سال: 2012

ISSN: 1939-4551

DOI: 10.1097/01.wox.0000411832.77376.7d